Researchers Found Drug Which may protect Obese and Diabetic women from coronavirus

The deadly virus which is trending over the world, has being proven by some researcher not to affect some group of persons which is the women.

A drug commonly taken to treat the chronic condition offered protection. Metformin is commonly prescribed to counteract the overproduction of sugar by the liver and to improve the body’s response to insulin.

It’s typically a first line of treatment for people diagnosed with type 2 diabetes, including some 30 million Americans. Metformin is the fourth most commonly prescribed drug in the US, according to Mayo Clinic.

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At the University of Minnesota, researchers hoped that the drug can treat risk factors for severe or deadly coronavirus infection, also reducing the risks of these outcomes.  

From studies found, the drug reduced the risk that women would die of coronavirus by up to 24 percent, but it didn’t seem to confer the same protection for men.

Diabetic and obese women taking the blood sugar control drug, metformin, which costs about $16, saw lower risks of dying of coronavirus after being hospitalized for the infection.

People who are overweight or diabetic have higher levels of baseline inflammation. Often, it is out of control inflammation from a flailing immune response to coronavirus that kills COVID-19 patients, rather than coronavirus.

People who suffers higher levels of inflammation before they contact coronavirus are at a heightened risk of getting severely ill or dying from the infection.

In the absence of a treatment designed specifically to counteract coronavirus itself, or a vaccine to prevent infection, scientist have been testing various existing medications, including antivirals that might interfere with coronavirus’s ability to make copies of itself, as well as inflammation-fighting drugs. 

Insulin resistance that characterizes diabetes leads to the buildup of sugar, or glucose in the blood, both of which lead to inflammation.

Metformin helps to manage blood sugar levels, and thus inflammation levels.

There were 15,380 people hospitalized with coronavirus and enrolled in the study. Of them, 6,256 had been diagnosed with either diabetes or obesity. Of the diabetic or obese patients, 2,333 had metformin prescriptions.

Women who were on metformin were 21 to 24 percent less likely to die of the infection – a statistically significant reduction in risks. It’s not entirely clear why women would see such benefits, but men would not.

However, it’s hardly the first sex difference reported in coronavirus severity.

Across the board, men are more likely to become severely ill or die from the disease, though the exact disparity varies from study to study and region to region.

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